lâm sàng nghiên cứu Collection | A wearable EEG-based Assistive BCIs System for phục hồi chức năng sau đột quỵ - đột quỵ Center

nghiên cứu background
The combination of BCI and auxiliary robot is a new điều trị for phục hồi chức năng sau đột quỵ. However, most of the existing nghiên cứu is based on complex system setups, expensive and bulky equipment. In this nghiên cứu, a wearable EEG brain-computer interface system for bàn tay function phục hồi chức năng is designed to do clinial trial. This system is composed of customized EEG cap, commercial amplifier, and bàn tay exoskeleton. In addition, the system includes the visual interface for the convenience of users. The trial enrolled six healthy participants and two đột quỵ bệnh nhân to verify the safety and hiệu quả of the system.

Method

To verify the safety and hiệu quả of the system, 6 healthy subjects(1 female and 5 males, aged 23±3 years old) from Shanghai Jiao Tong University and 2 đột quỵ bệnh nhân(all right bàn tay affected) from the phục hồi chức năng department of Huashan Hospital were recruited to participate in the nghiên cứu. A 6-minute training session was conducted for each subject, in which the subjects performed right-bàn tay vận động execution(đột quỵ bệnh nhân’s affected bàn tay to make a chuyển động attempt) according to visual cues. A red rectangle appears on the right or center of the screen, indicating action execution (or attempt) or rest, respectively. The task lasts for 4 seconds until the white cross disappears. It is recommended that healthy subjects repeat clenching and extending fists 3-4 times, and đột quỵ bệnh nhân are instructed to make vận động attempts during vận động tasks. The online test was similar to the training session, except that all red rectangles appeared in the center of the screen, which allowed subjects to choose to move their bàn tay (or exercise attempt) or rest at will. Test kết quả are provided to users visual and proprioceptive phản hồi via a screen and bàn tay exoskeleton shortly after task completion. There are three online test runs, each containing 20 trials. Each subject may rest between runs. All subjects were asked to refrain from any additional facial or cánh tay cơ chuyển động throughout the experiment.

kết quả

The average accuracy of offline and online training is 84.91% and 79.38%, respectively. Seven subjects had online accuracy of more than 70%, five more than 80%, and one more than 90%.

The Event-related Spectral Perturbation(ERSP) showed that the sensorimotor cortex was activated in both α and β bands during right bàn tay chuyển động training, with stronger activation on the same side. Meanwhile, as expected, the uncontrolled state showed no significant activation on either the C3 or C4 channels. In the online test, both the left and right hemispheres were activated to perform right-handed movements.

 

Conclusion

This nghiên cứu demonstrates a wearable brain-computer interface system for bàn tay function phục hồi chức năng after đột quỵ. The kết quả of vận động task differentiation preliminarily confirm the feasibility of this thiết bị, which shows great lâm sàng application potential.

Reference: Qin Z, Xu Y, Shu X, et al. eConHand: A Wearable Brain-Computer Interface System for phục hồi chức năng sau đột quỵ[C]// 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2019.